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HaDPop revision


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[Front]


What is the definition of a census and what is it useful for
[Back]


A simultaneous collection of demographic data of people at a specific area Useful for : Allocation of resources To see trends in a population Projection of the population

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What is the definition of a census and what is it useful for
A simultaneous collection of demographic data of people at a specific area Useful for : Allocation of resources To see trends in a population Projection of the population
What is crude birth rate
Number of live births per 1000 population
What is General Fertility Rate
Number of live births per 1000 fertile women between the ages 14-55 ( better for calculating birth rates )
How do you calculate the relative risk ( basic formula )
Incidence risk of exposed group / incidence risk of unexposed group
How do you calculate Point prevalence
Number of cases at that time / Number of people at that time
How do you calculate Incidence Risk
Number of new cases in that specific time / Number of disease free people in that time
What is a confounding factor
A factor that is associated with both the outcome and exposure of intrest
How to calculate Standardised Mortality Rate
Observed number of deaths/ expected number of deaths x 100
How do you calculate Incidence Rate
Number of new cases in a time period / (Number of total people x Follow up period)
How do you calculate Odds of exposure
Exposed cases / Unexposed cases
How do you calculate Odds Ratio
Odds of exposure in cases / Odds of exposure in control
What are some advantages of Case control Studies
Good for rare disease or long time for a disease to develop Requires small sample size Overcomes temporal delays Cheap and quick
Advantages of Cohort Studies
Good for rare exposures Possible to measure the incidence/risk directly Reduced recall and selection bias
Disadvantages of Cohort Studies
Takes a long time Large and resource intensive Risk a high losses of follow up --> survivor bias Not good for rare diseases
Disadvantages of Case Control Studies
Only possible to calculate OR Recall, Selection and Information Bias Sometimes difficult to be sure that exposure preceded disease
Advantages of RCT
Unbiased distribution of confounders Blinding Randomisation Results are accurate becuase control group is used Can make causal interferences
Disadvantages of RCT
Expensive --> time/money Volunteer Bias Ethically problematic at times
How can you spot Publication Bias in a systematic review or meta-analysis
Use a funnel plot, where you put the study size and whether it worked or not and see if there are any gaps
How do you interpret Forests Plots
Bigger the dot, the bigger the sample used The line is the confidence interval while the vertical line intersecting with the lines of the plots show the Odds ratio ( position of the box ) - Basically if there is an intersection then the data is not statistically significant
What is Bradford Criteria used for?
Inferring causality Uses features such as association features, Exposure/outcomes and Other evidence
Advantages of systematic reviews
Avoids duplication of studies High statistical power High quality evidence Useful when there are disparate findings among several studies
Disadavantages of systematic reviews
Publication bias Requires access to various databases Vairable quality of studies
How do you interpret the Confidence Interval
You look at whether the range of values of the CI has the null value of 1, if it does that means that you cannot reject the null hypothesis Hence the data is statistically significant