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Science Term 1 2021 Year 10 - DNA


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Aaron Smith


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[Front]


Who was Gregor Mendel/What did he do?
[Back]


He was the man of science, planted plants and obserced their growth. Father of genetics because he gave us the fundamental teachings of genetics.

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Who was Gregor Mendel/What did he do?
He was the man of science, planted plants and obserced their growth. Father of genetics because he gave us the fundamental teachings of genetics.
What is one core principle Mendel discovered?
Principle of Independent Assortment - Inheritance of one trait has no effect on the inheritance of another
What are genetics?
The study of traits passed on from previous ancestors or parent to offspring.
What determines a trait?
Genes, which are on the chromosomes.
DNA is the...
Blueprint of life, the code different to every individual.
What do Base pairs do?
They pair to create code.
What are Pyrimidines?
They are the base pairs of Cytosine and Thymine
What are Purines?
They are the base pairs of Guanine and Adenine
DNA is directional, what does this mean?
It means each strand of a DNA molecule run next to eachother, but in opposite directions.
A gene is...
A segment of DNA that codes for a protein
What are amino acids?
Tiny chemicals that are in different shapes and go together in a variety of builds. In short, the building block of life.
What is the sequence of creation of life?
DNA creates RNA which tells a Ribosome how to create a protein, and protein creates life.
What do the three letters of RNA do?
Tell the ribosome what combination to create for a specific protein,
What does the Ribosome do after reading 3 letters of RNA?
It sucks amino acids from the surrounding and puts them together to build the protein.
Where does the RNA go after leaving the nucleus?
Into a particle - the Ribosome, which reads RNA 3 letters at a time.
How does DNA interact with the cytoplasm?
RNA creates a partial copy of the DNA which are only one strand, this makes them small enough to slip through the pores of the nucleus.
Where do Amino Acids live?
Inside the cytoplasm
What do amino acids go together to create?
A variety of proteins, e.g. proteins to make tissue/organs.
What is an Allele?
Variations of genes
What does a punnet square represent?
The possible outcomes of different phenotypes represented through genotype alphabets.
What are genotypes?
The types of genes represented in alphabets
What is a Phenotype?
They are physical traits eg. colour of hair
What is a homologous pair?
The pair in which chromosomes come
What is the leading strand and lagging strand?
There is one strand in which DNA Polymerase can replicate faster, that is called the "leading strand", the other is called the "lagging strand" because it is slower.
What is an Okazaki fragment?
They are the fragments left on the lagging strand from DNA polymerase starting and ending in fragments. Ligase has to fill them with a glue to complete the strand.
What direction can DNA Polymerase travel?
Only from 5' prime to 3'prime direction.
What do SSB proteins do?
Bind the DNA strands to maintain their separation during the replication process.
What is the role of Ligase?
To fill any gaps on the "Lagging strand" so that the DNA strand is complete.
What is the role of Primase?
To create a primer for the DNA Polymerase to know where to begin/end.
What is the role of Helicase?
To "unzip" the DNA and break the Hydrogen bond.
What are the key enzymes in the replication of DNA?
DNA Polymerase, Helicase, Primase and Ligase
Why is DNA replication essential?
It is necessary for the creation of new cells so they may create more cells in the future.
What is the rold of DNA Polymerase?
To replicate the DNA molecules and build a new strand.
What is one of the most important parts in Prophase 1
"crossing over" aka the sharing of genes on chromosomes
Meiosis occurs over...
Two cell divisions
What is the process of meiosis?
The creation of sperm in males and eggs in females. (production of gametes)
What are the phases of mitosis?
Interphase, Prophase, Metaphase, Anaphase, telophase and cytokinesis
What happens in the "Interphase"
This is the cell recognising that it needs to split, chromosomes appear as chromatin threads, dna replicates and by the end of interphase chromosomes will have split into chromatins.
What happens in Prophase?
Preparation of splitting, nucleus breaks up and chromatids are ready to go. Protein spindles form.
What happens in Metaphase?
Chromosomes beging migrating to the equator of the cell, and spindles attach to the centromere of each chromosome
What happens in Anaphase?
Chromatids seperate and are pulled to the poles of the cell by spindles.
What happens in telophase?
Chromatids reach poles and become chromosomes, a nuclear membrane is formed around each bundle of chromosomes, chromosomes uncoil reverting to chromatin thread.
What happens in Cytokinesis
The finalisation - the splitting of the cytoplasm ect.
What are chromosomes?
Compact DNA in a cell.
How do chromosomes duplicate?
They duplicate to form two chromatids, but they are still recognised as one single chromosome until they split.