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Cell Biology


🇬🇧
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Maren Morgan


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[Front]


adherens junctions transmembrane proteins
[Back]


Cadherin

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Cell Biology - Details

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Adherens junctions adapters
P120, alpha and beta catenin, vanculin
Focal Adhesion adapter
Talin, kidlin, vinculin
Desmosomes cytoskeletal element
Intermediate filament
Adherens junctions purpose
Cell-cell adhesion
Desmosome purpose
Cell-cell adhesion
Focal adhesion
Cell-ECM adhesion
Hemidesmosome purpose
Cell-ECM adhesion
Gap junction purpose
Allow movement between cells
Tight junction purpose
Prevent movement between cells
Myosin (I) structure (3)
Plus, nonprocessive, 1 head
Myosin (II) structure (3)
Plus, nonprocessive, 2 heads
Myosin (V) structure (3)
Plus, processive, 2 heads
Myosin (VI) structure (3)
Minus, processive, 2 heads
Kinesin structure (3)
Plus ended, processive, 2 heads similar to actin
Dynein structure
Minus ended, processive, 2 heads, stalk, neck, tail
Myosin ATP binding
Release from actin
Myosin ADP release
Bind and power stroke
Kinesin ATP binding
Power stroke and cocking
Kinesin ATP hydrolysis
Release from microtubule
Kinesin ADP release
Caused by binding
Dynein ATP binding
Release and extension
Dynein ATP hydrolysis
Binding and power stroke
Cap Z
Binds plus end of actin, prevents addition
Tropomodulin
Binds minus end, prevents removal
Tropomyosin
Stabilizes actin fibers
Cofilin
Forces actin fiber breakdown
Thymosin
Binds actin monomer, prevents addition
Profilin
Binds actin monomer increasing addition
G-actin
Monomer for actin
F-actin
Polymer for actin
Formin
Works with profilin, stabilizes G-actin, increases addition
Microtubule monomers
Alpha and beta tubulin
Gamma tubulin
Removes nucleation, place for dimers to add to
Microtubule GTPase
Beta tubulin
Kinesin-13
Slows addition, enduces catastrophe, destabilization of protofillament
XMAP215
Increases growth, slows catastrophe, stabilization of protofillament
Cillia/Flagella
Microtubules 9+2
Centrioles
Microtubules 9+0
Keratin (I& II)
Acid and base, give strength to epithelium, provide structure for hair, fingernails, scales
Vimentin III)
Widely expressed, creates junctions with other cells, involved in cell signalling
Neurofilaments (IV)
Help axon grow and strengthen it
Lamins (V)
In nucleus, can make a meshwork
Nestin (VI)
In axons, regulate axon width