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Pharmacology for Nurses II - Anti-infectives

In English

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Michael Collins

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Penicillin (antibacterial)

Penicillin G: Class

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Pharmacology for Nurses II - Anti-infectives - Details



160 questions
Penicillin (antibacterial)
Penicillin G: Class
Inhibition of cell wall synthesis, Bactericidal
Penicillin G and Cephazolin: Mechanism of Action
Tetracycline (antibacterial)
Tetracycline: Class
Inhibition of protein synthesis, Bacteriostatic
Tetracycline: Mechanism of Action
Macrolide (antibacterial)
Erythromycin: Class
Broad spectrum
Gentamicin: Spectrum
Watch for serious adverse effects
Ciprofloxacin: Nursing Implications
Sulfonamides (antibacterial)
Trimethoprim-Sulfamethoxazole: Class
Inhibition of metabolic pathways (folic acid metabolism), Bacteriostatic
Trimethoprim-Sulfamethoxazole: Mechanism of Action
Trimethoprim-Sulfamethoxazole: Indication
Rash; allergy; blood disorders; renal tubule damage
Trimethoprim-Sulfamethoxazole: Side Effects
Acyclovir: Class
Oseltamivir: Class
Polyene antifungal
Amphotericin B: Class
Serious systemic fungal infections
Amphotericin B: Indication
Fluconazole: Class
Mycolic acid inhibitor
Isoniazid: Class
TB prophylaxis and treatment
Isoniazid: Indication
Penicillin G: Class
Penicillin (antibacterial)
Penicillin G and Cephazolin: Mechanism of Action
Inhibition of cell wall synthesis, Bactericidal
Penicillin G: Spectrum
Narrow spectrum, more effective for gram(+)
Penicillin G: Indication
Used for syphilis, meningitis, endocarditis, pneumonia
Penicillin G and Cefazolin: Side Effects
Hypersensitivity includes rash and anaphylaxis; Minor GI disturbances and diarrhea
Penicillin G: C/C
Most common drug allergy; renal impairment
Penicillin G: Nursing Implications
Check patient history for allergy; Unstable in stomach acid - parenteral route; Resistance continues to grow
Cefazolin: Class
Cephalosporin (antibacterial)
Cefazolin: Indication
Used for infections of respiratory, urinary biliary, bones and joints, gonorrhea, septicemia; 1st line for surgery prophylaxis
Cefazolin: C/C
Do not give to patients w/ life-threatening penicillin allergy; caution with renal impairment
Cefazolin: Nursing Implications
Surgery prophylaxis - should be given within 60 minutes of "cut" time
Vancomycin: Class
Vancomycin (antibacterial)
Vancomycin: Mechanism of Action
Inhibition of cell wall synthesis - binds to the cell wall, Bactericidal
Vancomycin: Indication
Severe infections resistant to safer antibiotics (e.g. MRSA infections resistant to fluoroquinolones, C. Diff, meningitis)
Vancomycin: Side Effects
Ototoxicity - can be irreversible; Renal toxicity; Red man syndrome (flushing, tachycardia, hypotension); Thrombophlebitis at IV injection site
Vancomycin: C/C
Hypersensitivity to drug; impaired renal function; history of hearing loss; doesn't mix with other IV drugs
Vancomycin: Nursing Implications
Own IV line if possible; monitor infusion site for extravasation
Tetracycline: Class
Tetracycline (antibacterial)
Tetracycline: Mechanism of Action
Inhibition of protein synthesis, Bacteriostatic
Tetracycline: Indication
Drugs of choice for typhus, cholera, Rocky Mountain spotted fever, Lyme disease, H. pylori ulcers, and chlamydia