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level: 17.5 Codominance and multiple alleles

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level questions: 17.5 Codominance and multiple alleles

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Mutiple alleles (+ codominance) the ABO blood system- Controlled by tri-allelic gene - Can generate 6 pehnotypes - The alleles control the production of the antigens on the surface of the red blood cells - Two of the alleles are codominant to one another and both are dominant over the third - Allele IA produces antigen A - Allele IB produces antigen B - Allele IO produces no antigen
6 phenotypes- IAIA A - IBIB B - IAIB AB - IOIO O - IBIO B - IAIO A
Symbols for codominance alleles- Both alleles expressed in the heterozygous both take a capital case letter - An index letter (small at the top) indentifies the allele - Therefore: normal haemoglobin alleles is Hb (small N) - Siclcle cell allele is Hb (small S) Hbn Hbs = resistence to malaria