level: MODE OF ACTIONS OF DRUGS
Questions and Answers List
level questions: MODE OF ACTIONS OF DRUGS
| Question | Answer |
|---|---|
| EMETINE & DEHYDROEMETINE MOA | 1 Inhibit peptidyl-tRNA translocation, Inhibits Protein Synthesis |
| ATOVAQUONE MOA | 1 collapses plasmodial mitochondria membranes → interferes with ATP production. |
| Nifurtimox MOA | Undergoes reduction and generates intracellular oxygen radicals (superoxide radicals and hydrogen peroxide) |
| Sodium Stibogluconate MOA | Inhibit phosphofructokinase in the parasite |