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level: Level 9 - TABLET COATING

Questions and Answers List

level questions: Level 9 - TABLET COATING

Question	Answer
 INVOLVES SUCCESSIVE APPLICATIONS OF SUCROSE BASE SOLUTION to the tablet course in a suitable coating equipment  MORE PREFERRABLE THAN FILM COATING	Sugar coating
Sugar coating STEPS	1) Sealing: a separate care from water, through sealing we can make the tablet a water proofing tablet 2) Sub-coating: contour the tablets rapidly and its size and mixing the gelatin and acacia 3) Syruping: syrup coating of sucrose base solution on drying phase 4) Finishing: coloring of tablets in three to four coats 5) Polishing: done to canvas polishing wax solution 6) Printing: for identification purpose with special edible inks
 There Is a DEPOSITION usually by a SPRAY METHOD  USE A THIN FILM OF POLYMER TO SURROUND A TABLET COAT  INCLUDES THE POLYMER, PLASTICIZER, COLORANT, SOLVENT  As a RESULT, will have a LIGHTER TABLET compared to sugar coated tablets	Film coating
Problems in film coating:	1 Blistering 2 Wrinkling 3 Bridging 4 Sweating 5 Orange peel 6 Flaking 7 Bloom and spotting
1 causes REDUCE ADHESION BETWEEN THE FILMS and surface due to RAPID DRYING (bubble formation) 2 due to IMPROPER DRYING or FILM FORMER DEFECT	1 Blistering 2 Wrinkling (PROBLEMS IN FILM COATING)
1 bridging of monogram present in the tablet core 2 PRESENCE of the OILY FILMS and DROPLETS OF LIQUID in the film surface due to incompatibility	1 Bridging 2 Sweating
1 ROUGHNESS IN THE SURFACE because of PREMATURE DRYING of anatomize droplets of solution or STRAINING TWO VISCOUS COATING SOLUTION 2 due to RAPID DRYING BETWEEN the COATS 3 due to the CONDITION of MIGRATION of PLASTICIZER TO SURFACES	1 Orange peel 2 Flaking 3 Bloom and spotting (PROBLEMS IN FILM COATING)
TABLET COATING Other new concepts:	A. Electrostatic coating B. Laminated coating El La
 employed to APPLY FILMS TO CONDUCTIVE MATERIALS by IMPARTING AN IONIC CHARGE to the SUBSTRATE; an OPPOSITE CHARGE to the COATING MATERIALS  ENSURE as THIN & CONTINUOUS FILM ON THE SURFACE	A. electrostatic coating
 PROVIDES A SECOND ACTION OR LAYER OF MEDICAMENT for the TABLET then it is USED AS CIRCUIT ACTION TABLET, ENTERIC or BUCCAL TABLET	B. Laminated coating
BASIC PROCESSES used in Application of coating:	1. Pan coating 2. Air suspension coating 3. Dip coating 4. Tablet compression coating PAD T
 A PROCESS in which USED IN A BULK SUGAR AND FILM COATING  MOSTLY USED IN THE INDUSTRY	Pan coating
 MOST DEPENDABLE METHOD in applying film coat  Ex. Fluidized bed coater	Air suspension coating
 MATERIALS TO BE COATED are usually PLACED IN THE BASKETS & DIP in the CONTAINERS of a COATED SOLUTIONS	Dip coating
 It is DONE BY THE SPECIAL DOSAGE FORM  If you want to MAKE A TABLET FROM TWO INCOMPATIBLE DRUGS  The two incompatible drugs may be separated by placing one in the core and in the coating	Tablet compression coating