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Cytology

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Question:

Talk about import of protein mechanism.

Author: H K



Answer:

Proteins are post-translationally imported towards the mitochondria. It is possible due to the presence of a certain address code whose named presequence or targeting sequence, located near N-terminus of polypeptide chains and contains a number of positively charged presequence and mediates with the help of chaperons HSP proteins, translocation towards the mitochondria through the TOM and TIM (translocases) complexes present in OMM and IMM respectively, they are multisubunit channels specialized in import to mitochondrion, presequence is removed after delivery by proteases of mitochondria.


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H K
H K