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Physiology

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Question:

Describe the coronary metabolism in regards to coronary circulation

Author: Donata Nshimyicizanye



Answer:

Myocardial ATP production is ~95% from metabolism. Resting myocardial energy demand is approximately 20-fold that of skeletal muscle. To maintain O2supply, O2extraction in cardiac tissue is ~75%. As a result, increase in O2demand during exercise are mediated primarily by increases in coronary blood flow


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