Explain the steps of intracellular signaling

1. Signal known as first messenger is synthesized then transported to tearget cell 2. Upon receiving the signal ( growth factor ) , a membrane bound receptor become activated 3. Then results in activation of second messenger(s) which transmit the signal further downstream . As to transmit the signal further downstream the activated receptor passes the signal onto components signal use. Signaling proteins which can be activated or deactivated. 4. This then result in changes of cellular metabolism which then elicit response required by cell such as proliferation , survival , hypertrophy and so on. 5.Then signal attenuated which then terminates the response .