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Filtration and Reabsorption

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Question:

What channels does the ascending loop of henle contain

Author: Lapras Fan



Answer:

The TAL consists of simple cuboidal epithelial cells that lack aquaporin-1 channels therefore the TAL is relatively impermeable to water Na+/K+ ATPase pumps in the basolasteral membrane create an electrochemical gradient that allows reabsorption of Cl– by Na+ /Cl– symporters in the apical membrane Leads to the formation of hypotonic fluid


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