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From course:

Introduction to Infection

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Question:

Mechanism of infection of Cholera toxin

Author: Lapras Fan



Answer:

Has 2 subunits A / B 1. One of the B subunits bind to the glycoprotein receptor resulting in cleavage of the A subunits 2. The A part enters the cell cytoplasm and activates adenylate cyclase 3. Adenyl cycalse converts ATP into cAMP 4. The cAMP stimulates secretion of electrolytes from the cell into the lumen 5. Water typically flows towards the highest conc. of electrolytes so water leaves resulting in diarrhoea


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