Formation of root hair from the root epidermis

Werewolf (WER) encodes a transcription factor expressed in non-hair cell. Initially all epidermal cells express WER. WER turns on GL2, which maintains cells in a non-hair (NH) state. Root hair differentiation is triggered by a signal from a protein called JACKDAW (JKD) in cortical cell. This results in inhibition of Werewolf (WER) expression. GL2 expression is switched off, leading to differentiation into a hair cell (H). Non-hair cells express CAPRICE (CPC), which migrates to hair cell to inhibit expression of WER.