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Bacteriology

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Question:

How does protein A contribute to the virulence of staph aureus?

Author: H K



Answer:

IgG antibodies have an Fc portion and a Fab portion (attaches to the antigen). The Fc portion is important in the phagocytosis mediated by antibody opsonization. However, if the protein A is attached to the Fc portion, it will replace the phagocyte and help the Staphylococcus Aureus avoid phagocytosis and its destruction by phagocytic cells.


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H K
H K