Talk about bacteriophage mediated resistance

. The Panton-Valentine Leucocidin (PVL) gene for example is an exotoxin virulence factor. It destroys the white blood cells. In the nucleoid, the genetic material is integrated, and the bacteria starts secreting the PVL toxin. At the same time, through transformation (taking genetic material from a dead bacteria), staph can acquire the mecA gene and develop methicillin resistance.