7.5 mg/kg q12h IM or 15 mg/kg/d IV divided into two to three equal doses given slowly. available in parenteral and oral forms, used to treat hepatic coma (and to decrease gastrointestinal (GI) normal flora) when ammonia- producing bacteria in the GI tract cause serious illness. adjunct therapy to  GI bacterial flora. Should not be used 7 to 10 days due to potential toxic effects like renal damage, bone marrow depression, and GI complications.