Third-Generation Cephalosporins: Dosage/Route: Adult: 500mg-2 g IM or IV q8-12h; reduce dose with renal impairment Pediatric: 50 mg/kg IM or IV q6-8h Usual Indications: Treatment of respiratory, gynecological, pelvic inflammatory, intra-abdominal, skin, and bone and joint infections; also used for sepsis and meningitis