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From course:

Unit 3 Part 2 - Ch 18: Gene Expression Regulation

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Question:

Positive Gene Regulation? Activator?

Author: AMRIT KAUR



Answer:

- Some operons are also subject to positive control through a stimulatory protein, called an activator of transcription​ - When glucose (a preferred food source of E. coli) is scarce, a specific activator attaches to the promoter of the lac operon and increases the affinity of RNA polymerase, thus accelerating transcription​ - When glucose levels increase, the activator detaches from the lac operon, and transcription returns to a normal, low level​ - The ability to catalyze compounds like lactose enables cells deprived of glucose to survive​


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- Some operons are also subject to positive control through a stimulatory protein, called an activator of transcription​
- When glucose (a preferred food source of E. coli) is scarce, a specific activator attaches to the promoter of the lac operon and increases the affinity of RNA polymerase, thus accelerating transcription​
- When glucose levels increase, the activator detaches from the lac operon, and transcription returns to a normal, low level​
- The ability to catalyze compounds like lactose enables cells deprived of glucose to survive​
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