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PHARM MED ORG

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Question:

1 Isoniazid is an analog of __ 2 Adverse Effects of Isoniazid 3 Adverse effects happen because Isoniazid competes with __ for the enzyme __ 4 Prevents Neurotoxicity even in higher doses of Isoniazid, but routine use is not mandatory. 5 Is treated with Vitamin B6 100mg / day.

Author: Dwight Obillos



Answer:

1 Pyridoxine (Vitamin B6) - a potent anti tubercular drug 2 a) peripheral neuritis b) Neurological manifestations: Paresthesia, Numbness, Mental disturbances, Optic neuritis, Convulsions c) Hepatitis (potentially fatal) - Due to Pyridoxine (Vit B6 Deficiency) 3 Pyridoxal phosphate, Apoptryptophanase 4 Vitamin B6 10 mg / day 5 Isoniazid Neurotoxicity


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