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BIO May Exam

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Question:

Proof for Singer-Nicholson model?

Author: Rebeca Lorena Arce Fonseca



Answer:

1. Freeze etched micrographs showed globular proteins in the middle of the membrane 2. Analysis of membrane protein showed parts of their surface were hydrophobic, so they would have to be within the bilayer 3. Fluorescent antibody tagging showed that membrane proteins tagged with red and green eventually fused after 40 mins, showing the fluidity of membranes


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