PHARMCARE 3: 1 Oxidation - REACTIVE METABOLITES - Structural GENE DAMAGE

2 structural changes in the DNA,
oxidation of the drugs produce reactive metabolites,
covalent interaction with DNA
Inheritable,
takes 10-40 YEARS to develop,
Anticancer drugs, radioisotopes,
Marketed for life threatening conditions

Question

1 Oxidation -> REACTIVE METABOLITES -> Structural GENE DAMAGE

2 structural changes in the DNA,
oxidation of the drugs produce reactive metabolites, 
covalent interaction with DNA
Inheritable, 
takes 10-40 YEARS to develop, 
Anticancer drugs, radioisotopes,
Marketed for life threatening conditions

LEIGHTON DWIGHT OBILLOS · Accepted Answer

1 Carcinogenicity

2 Mutagenicity

PHARMCARE 3

1 Oxidation -> REACTIVE METABOLITES -> Structural GENE DAMAGE 2 structural changes in the DNA, oxidation of the drugs produce reactive metabolites, covalent interaction with DNA Inheritable, takes 10-40 YEARS to develop, Anticancer drugs, radioisotopes, Marketed for life threatening conditions

1 Carcinogenicity 2 Mutagenicity

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