How is the presentation of DI?

Most pt have intact thirst mechanism (no dehydration but polyuria and polydipsia (increased thirst)) Severe hypernatremia (not observed in pt with DI because of intact thirst), however pt with inadequate thirst response can rapidly become dehydrated and develop hypernatremia Hypertonic (hypernatremic) encephalopathy (coma, shrinkage of brain, seizures) may occur due to secretion of intracellular water towards outside where we have hypernatremia. Decreased brain volume (subarachnoid hemorrhage, intracerebral bleed, petechial hemorrhage)