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TOXICOLOGY

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Question:

(A. TOXICANT-INDUCED CELLULAR DYSREGULATION) 2) Dysregulation of Signal Transduction Chemically Altered Signal Transduction with Proliferative Effect: 1 Xenobiotics that FACILITATE PHOSPHORYLATION of signal transducers often PROMOTE __ 2 __ may also be activated by interacting proteins that had been altered by a xenobiotic. 3 Aberrant phosphorylation of proteins may result from DECREASED DEPHOSPHORYLATION by __.. 4 Inhibition of phosphatases = __

Author: LEIGHTON DWIGHT OBILLOS



Answer:

. 1 mitosis and tumor formation 2 Protein kinases 3 phosphatases. 4 Mitogenic effect of various chemicals, oxidative stress, and ultraviolet (UV) irradiation.


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