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CNS Pharmacology

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Question:

L. Pregabalin

Author: Suzuki



Answer:

Pregabalin binds to the α2-δ site, an auxiliary subunit of voltage-gated calcium channels in the CNS, inhibiting excitatory neurotransmitter release. The exact role this plays in treatment is not known, but the drug has proven effects on partial onset seizures, neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia.


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Author

Suzuki
Suzuki