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A+P Connective Tissue


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John Nixon


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[Front]


Reticular Tissue
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-slender branching web + reticular cells -spleen + lymph nodes -filter, then phagocytosis

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A+P Connective Tissue - Details

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Reticular Tissue
-slender branching web + reticular cells -spleen + lymph nodes -filter, then phagocytosis
Adipose CT
-Richly vascularized -many cells, little matrix -Fetus-brown adipose tissue+more mitochondria
Areolar CT
-Loose fibrous ct- fibroblasts+macrophages -stretchable -absorbs fluid during inflammation, causing edema
CT types (5)
Loose fibrous, dense fibrous, blood, bone, cartilage
Elastic Fibers
"yellow fibers" -Elastin+fibrillin -stretch 150% of length -external ear, skin, lungs, BV
Reticular Fibres
-Delicate fine net of Reticulin -nerves, filters, capillaries
Collagen Fibres
-Strongest, pliable, resists pulling -most common
Hyaluronidase
Breaks down hyaluronic acid, makes CT liquidy -used by pathogens, sperm, and WBC
Hyaluronic Acid
-in ground substance -slippery polysaccharide -joints, eyeballs
Dermatan Sulphate
-CT of BV, heart valves, skin, tendons
Macrophages
-dev. from monocytes (WBC) -Phagocytic -irregular shape, short branches
Endoderm
Becomes epithelial cells
Mesoderm
Becomes epithelial, muscle, connective tissue cells
Ectoderm
Becomes epithelial, nervous tissue cells
Fibronectin
Main cell adhesion protein of CT
CT structures (3)
Matrix, fibres, cells
Mature cyte functions
Maintenance, decreased ability to divide
Fibroblasts
Loose Fibrous CT + dense fibrous CT -branched, large, flat -migrate and secrete
Plasma Cells
Dev. from B-lymphocte -antibody production to blood+tissues -Ab=specialized protein- binds to foreign cells
Mast Cells
BV in CT -Migrate to tissue+release histamine-dilates sm BV ^ local blood supply -inflammation and healing
Adipocytes
-fat cells, store triglycerides -below dermis + around organs -fat contained in vacuole
Glucosaminoglycans (GAG)
Polysaccharide associated with proteoglycans
Proteoglycans
Proteins that bind h2o to change tissue consistency
Keratan Sulphate
Bone, cartilage, CT of cornea
Chondroitin Sulphate
Support+adhesion cartilage, bone, skin, BV
Ground substance
Interstitial fluid, cell adhesion proteins, proteoglycans
CT matrix
-ground substance + fibres
Dense Regular Fibrous CT
-Fibres dominant + thicker -fibroblasts produce ground substance + fibres -closely packed collagen fibres, creates white flexible structure -tendons, aponeuroses, ligaments
Dense Irregular fibrous CT
-thicker collagen fibres arranged to resist in more than one direction -dermis, pericardium, heart valves, perichondrium, periosteum
Elastic CT
-Elastic Fibres -yellowish -fibroblasts dominant -lung tissues, arteries, ligaments
Cartilage
-Chondrocyte -avascular, non-innervated- slow to heal -flexible + tough due to collagen+elastic fibres chondroblasts make new matrix until skeleton complete -chondroblasts grouped in Lacunae (sm cavities)
Hyaline Cartilage
-clear/blue-white -most abundant, weakest -chondrocytes 1-10% of tissue volume -trachea, bronchi, ends of long bones, EPIPHYSEAL PLATES
Elastic cartilage:
-elastin fibres -repeated bending w/o breaking -external ear and epiglottis
Fibrocartilage
-Strongest, most durable cartilage -chondrocytes & collagen fibres -intervertebral disks, menisci of knee joint, tendons
Cartilage Growth-Interstitial
- # of chondroblasts increases, matrix increases - matrix pushes chondroblasts apart, expansion -childhood & adolescence
Cartilage Growth-Appositional
-perichondrium cells cause growth of cartilage -new cartilage is at the outer edges of the original cartilage (deposits apically) -later in life and continuous through adolescence
BONE
-composed of collagen (organic component) + mineral salts (inorganic component) -Bone salt = 65% of matrix -support, movement, mineral reservoir -highly vascularized
Osteoblasts
Bone-forming cells
Osteoclasts
Bone-resorbing cells
BLOOD
LIQUID tissue that contains NO ground substance and NO fibres -plasma, RBC, WBC, platelets
Haematopoiesis
Blood-forming activity