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Animal Histology

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Question:

Talk about thrombopoiesis.

Author: H K



Answer:

Platelets formation, regulated by stimulating factor (thrombopoietin). Myeloid--> Megakaryoblast (basophilic cytoplasm rich in ribosomes)-->DNA replicates many times without cell division making the promegakaryocyte then formation of basophilic megakaryocyte with gaint lobed nucleus (polyploidy)-->cytoplasm is enriched with granules and becomes the thrombocytogenic megakaryocyte (large cell with huge nucleus, membrane extensions called pro platelet territories (4-8) later fragmented to make 1000 - 1500 platelets to release in a sinusoid of red bone marrow.


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H K
H K