MDMA

- MDMA inhibits the reuptake of serotonin into the presynaptic neurone by binding to the specific proteins that enable serotonin reuptake, located on the presynaptic membrane; this increases the amount of serotonin present in the brain - Serotonin is usually reabsorbed into the presynaptic neurone to be recycled for future action potentials - MDMA also triggers the release of further serotonin from presynaptic neurones, further adding to the increase