Other severe toxicity 1 happened in 1992 2 happened in 1999

1 Temafloxacin syndrome - discoloured urine - jaundice, nausea, vomiting - abdominal pain - coagulopathy - hepatic and renal dysfunction 0.056% incident, 2 Trovafloxacin syndrome - Laboratory abnoormalities (ALT, bilirubin, encephalopaties, Necrotic inflammation) 0.0056% incidence 5 transplants 6 deaths