Cellular Changes:as the cell ages the plasma membrane has an increase amount of fatty acids. This structural change decreases the fluidity of the plasma membrane and reduces the transportation of the ions, nutrients, amino acids, and proteins across the membrane. Nuclear changes-as cell ages cross linkages form between the sulphur atoms on the DNA in the nucleus of the cells . This structural change condenses the DNA which decreases the synthesis of RNA reduces the cell ability to repair enzymes and may reduce cell's ability to divide. Cytoplasmic Change- as the cell ages the volume of cytoplasm increase enzymes that synthesize DNA move from the nucleus to the cytoplasm and there is a gradual build of lipofuscin. While its unclear how this directly affects the cell it is know that once the DNA migrate from the nucleus it is unable to synthesizes enzymes. Ribosomal Changes: the cell ages the amount of ribosomal decreases. this structural change results in a decreased level of protein synthesis